19,637 research outputs found

    Zeroes of partial sums of the zeta-function

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    This article considers the positive integers NN for which ζN(s)=∑n=1Nn−s\zeta_{N}(s) = \sum_{n=1}^{N} n^{-s} has zeroes in the half-plane ℜ(s)>1\Re(s)>1. Building on earlier results, we show that there are no zeroes for 1≤N≤181\leq N\leq 18 and for N=20,21,28N=20, 21, 28. For all other NN there are infinitely many zeroes.Comment: 5 Pages - Final Version will appear in LMS JC

    How do people with a mental health diagnosis construct an identity?

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    Psychiatric diagnosis is used to categorise and treat mental health problems in the UK yet is widely criticised for struggling to convincingly categorise the experience of distress and that it is socially constructed from the culmination of historical and cultural interactions. Service-user accounts are varied and there is a paucity of qualitative research that considers the positive and negative effects of labelling. To understand identity construction in the context of a psychiatric diagnosis, the present study recruited 16 participants from a service-user research group and five focus groups were conducted. Transcripts were studied using Foucauldian Discourse Analysis. Two major identities were detected ‘illness identity’ and ‘recovery identity’. Participants drew on multiple and competing discourses and which placed them in the position of patient and/or survivor. Medical discourses were dominant throughout the focus groups and were used in a way to convey the fluidity of the identity and how they related to their diagnosis. The study’s limitations are discussed, together with implications for clinical practice and future research

    How pharmacoepidemiology networks can manage distributed analyses to improve replicability and transparency and minimize bias

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    Several pharmacoepidemiology networks have been developed over the past decade that use a distributed approach, implementing the same analysis at multiple data sites, to preserve privacy and minimize data sharing. Distributed networks are efficient, by interrogating data on very large populations. The structure of these networks can also be leveraged to improve replicability, increase transparency, and reduce bias. We describe some features of distributed networks using, as examples, the Canadian Network for Observational Drug Effect Studies, the Sentinel System in the USA, and the European Research Network of Pharmacovigilance and Pharmacoepidemiology. Common protocols, analysis plans, and data models, with policies on amendments and protocol violations, are key features. These tools ensure that studies can be audited and repeated as necessary. Blinding and strict conflict of interest policies reduce the potential for bias in analyses and interpretation. These developments should improve the timeliness and accuracy of information used to support both clinical and regulatory decisions

    The effects on health of a publicly funded domestic heating programme: a prospective controlled study

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    <b>Objective</b>: To assess the effect of a publicly funded domestic heating programme on self-reported health. <b>Design, setting and participants</b>: A prospective controlled study of 1281 households in Scotland receiving new central heating under a publicly funded initiative, and 1084 comparison households not receiving new heating. The main outcome measures were self-reported diagnosis of asthma, bronchitis, eczema, nasal allergy, heart disease, circulatory problems or high blood pressure; number of primary care encounters and hospital contacts in the past year; and SF-36 Health Survey scores. <b>Results</b>: Usable data were obtained from 61.4% of 3849 respondents originally recruited. Heating recipients reported higher scores on the SF-36 Physical Functioning scale (difference 2.51; 95% CI 0.67 to 4.37) and General Health scale (difference 2.57; 95% CI 0.90 to 4.34). They were less likely to report having received a first diagnosis of heart disease (OR 0.69; 95% CI 0.52 to 0.91) or high blood pressure (OR 0.77; 95% CI 0.61 to 0.97), but the groups did not differ significantly in use of primary care or hospital services. <b>Conclusions</b>: Provision of central heating was associated with significant positive effects on general health and physical functioning; however, effect sizes were small. Evidence of a reduced risk of first diagnosis with heart disease or high blood pressure must be interpreted with caution, due to the self-reported nature of the outcomes, the limited time period and the failure to detect any difference in health service use

    Search, Moral Hazard, and Price Dispersion

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    We study the effects of insurance coverage on consumer search behavior and the pricing of services covered by insurance, constructing a general equilibrium model of moral hazard in search with an endogenous price distribution. When an insured event occurs, households request quotes from firms, who offer a homogenous service at various prices. We show that lower coinsurance rates reduce the amount of search by households, allowing firms to increase their prices. Hence, moral hazard in search is far more costly than shown in previous models, which ignored equilibrium firm response to changes in consumer search behavior.

    Control system for hunger and its implications in animals and man

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    Spin-triplet superconductivity in a weak-coupling Hubbard model for the quasi-one-dimensional compound Li0.9_{0.9}Mo6_6O17_{17}

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    The purple bronze Li0.9_{0.9}Mo6_6O17_{17} is of interest due to its quasi-one-dimensional electronic structure and the possible Luttinger liquid behavior resulting from it. For sufficiently low temperatures, it is a superconductor with a pairing symmetry that is still to be determined. To shed light on this issue, we analyze a minimal Hubbard model for this material involving four molybdenum orbitals per unit cell near quarter filling, using asymptotically exact perturbative renormalization group methods. We find that spin triplet odd-parity superconductivity is the dominant instability. Approximate nesting properties of the two quasi-one-dimensional Fermi surfaces enhance certain second-order processes, which play crucial roles in determining the structure of the pairing gap. Notably, we find that the gap has accidental nodes, i.e. it has more sign changes than required by the point-group symmetry.Comment: Update

    Migrant Farmworkers\u27 Perceptions of Pesticide Risk Exposure in Adams County, Pennsylvania: A Cultural Risk Assessment

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    Agricultural exceptionalism, a system in which regular labor laws and standards do not apply to farm labor, makes migrant farmworkers particularly vulnerable populations—economically, socially, and in terms of environmental health. To address inequities inherent in migrant farmworker margin­aliza­tion, studies advocate for actively engaging the migrant farmworker population in the conversation surrounding these issues. We conducted 40 semi­structured interviews with migrant farmworkers in Adams County, Pennsylvania, to understand pesti­cide risk exposure perceptions and practices. We employed the Health Belief Model as our cultural risk assessment frame, using it in combination with technical risk assessment, which uses government calculations (from the Environmental Protection Agency) to quantify pesticide risk exposure. We used mixed methods analyses (quantitative and qualitative) to compare and understand farmworker demographics, perceived risk, perceived control, and risk behavior. Results show that demo­graphics —e.g., age, education, visa status—are important factors in risk perception. They also confirm observations present in many earlier studies. While trainings and educational materials are valuable to help build awareness of risk, a systemic lack of control over their circumstances make it hard for migrant farmworkers to engage in safe behavior. Results also highlight the limitations of technical risk assessment. Such calculations, however, rarely account for risk perceptions and experiences of farm­workers themselves. Acknowledging the voices of migrant farmworkers is an essential first step in rebalancing inequities of power in our food systems, and cultural risk assessment can help frame recommendations that target different stake­holders across the pesticide regulatory spectrum to ensure migrant farmworker needs and safety

    Perceived characteristics of the environment associated with active travel: development and testing of a new scale

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    Background Environmental characteristics may be associated with patterns of physical activity. However, the development of instruments to measure perceived characteristics of the local environment is still at a comparatively early stage, and published instruments are not necessarily suitable for application in all settings. We therefore developed and established the test-retest reliability of a new scale for use in a study of the correlates of active travel and overall physical activity in deprived urban neighbourhoods in Glasgow, Scotland. Methods We developed and piloted a 14-item scale based on seven constructs identified from the literature (aesthetics, green space, access to amenities, convenience of routes, traffic, road safety and personal safety). We administered the scale to all participants in a random postal survey (n = 1322) and readministered the scale to a subset of original respondents (n = 125) six months later. We used principal components analysis and Varimax rotation to identify three principal components (factors) and derived summary scores for subscales based on these factors. We examined the internal consistency of these subscales using Cronbach's alpha and examined the test-retest reliability of the individual items, the subscale summary scores and an overall summary neighbourhood score using a combination of correlation coefficients and Cohen's kappa with and without weighting. Results Public transport and proximity to shops were the items most likely to be rated positively, whereas traffic volume, traffic noise and road safety for cyclists were most likely to be rated negatively. Three principal components – 'safe and pleasant surroundings', 'low traffic' and 'convenience for walking' – together explained 45% of the total variance. The test-retest reliability of individual items was comparable with that of items in other published scales (intraclass correlation coefficients (ICCs) 0.34–0.70; weighted Cohen's kappa 0.24–0.59). The overall summary neighbourhood score had acceptable internal consistency (Cronbach's alpha 0.72) and test-retest reliability (ICC 0.73). Conclusion This new scale contributes to the development of a growing set of tools for investigating the role of perceived environmental characteristics in explaining or mediating patterns of active travel and physical activity

    Detailed Geant4 simulations of the ANITA and ANITA-CUP neutron facilities

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    Simulations of the ANITA spallation neutron source at The Svedberg Laboratory (TSL) are described. Neutron radiation calculations show close agreement with measurements at both standard and close user positions. Gamma radiation characteristics are also predicted
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